ABSTRACT

Adrenal lesions are common in the general population, with reported rates approaching 10% particularly with increasing age. With the expanding use of imaging, the number of detected adrenal lesions has also risen. Although most are benign and of limited clinical significance, accurate characterization of hormonally active lesions or those with malignant potential is critical. The majority of cases can be correctly characterized with computed tomography and/or magnetic resonance imaging, and clinical management is shaped accordingly. Because endocrine evaluation both aids in diagnosing hormonally active lesions and influences treatment decisions, a multidisciplinary approach to adrenal gland pathology provides the greatest benefit for patients.